产品货号：
Z26801
中文名称：
SIRT2抗体
英文名称：
Anti-SIRT2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIRT2 Antibody |
| 指标别名 | SIR2;SIR2 like protein 2;SIR2L;SIR2L2;SIRT2;SIRT2-Specific |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SIRT2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human SIRT2(165-187aa YTQNIDTLERIAGLEQEDLVEAH),different from the related mouse and rat sequences by three amino acids. |
| 实际分子量 | 43KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SIRT2 is a predominantly cytoplasmic protein that colocalizes with microtubules.This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.SIRT2 is mapped to 19q13.2.It is able to cause radioactivity to be transferred from (32P) NAD to bovine serum albumin (BSA).According to researches,SIRT2 can act as a bona fide tubulin deacetylase.SIRT2 was found to deacetylate lys40 of alpha-tubulin both in vitro and in vivo.SIRT2 is also a regulator of mitotic progression that acts downstream from CDC14B in a pathway regulating mitotic exit or subsequent cytokinesis.What’s more,SIRT2 is an important regulator of programmed necrosis. |
| Uniprot ID | Q8IXJ6 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | sirtuin 2 |
| 蛋白名全称 | NAD-dependent protein deacetylase sirtuin-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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